mankhwala

23076-35-9, Xylazine hydrochloride

Kufotokozera Kwachidule:

Tsatanetsatane Quick

CAS Ayi: 23076-35-9
Mayina Ena: Xylazine HCl
Kufotokozera: MF: C12H17ClN2S
EINECS Ayi: 245-417-0
Malo Oyamba: China
Mtundu: Opangira Mankhwala
Chiyero: 99%
Dzina Brand: DUMI
Chiwerengero Cha Model: 23076-35-9
Ntchito: Animal Mankhwala
Maonekedwe: White ufa
Kachulukidwe: 1.15 g / cm3
Kulemera Kwa Maselo: 256.795
Misa Yolondola: 256.080109
Logarithmic: 3.51880
Yosungirako: Malo Ozizira Ndi Ouma
Kukhazikika: Khola Kutentha Ndi Kupanikizika

Mankhwala Mwatsatanetsatane

FAQ

Zogulitsa

Kugwiritsa ntchito Xylazine hydrochloride
Xylazine Hydrochloridendi α2 kalasi ya adrenergic receptor agonist.Cholinga: Adrenergic ReceptorXylazine ndi mankhwala omwe amagwiritsidwa ntchito poziziritsa, kutonthoza, kupumula kwa minofu, ndi analgesia mu nyama monga mahatchi, ng'ombe ndi nyama zina zopanda anthu. Analog ya clonidine, ndi agonist mgulu la α2 la adrenergic receptor. Xylazine posachedwapa yatulukira ngati mankhwala osangalatsa, makamaka ku Puerto Rico [1]. Kuyendetsa xylazine (0.17 mg / kg ya kulemera kwa thupi, kuchepetsedwa mpaka voliyumu ya 10-ml, pogwiritsa ntchito 0.9% NaCl) kumapangitsa pafupifupi maola 2.5 a analgesia am'deralo popanda zovuta zina. Mlingo wambiri wa xylazine unachititsa kuti kumbuyo kwa ataxia kofatsa. Kulamulira kwa lidocaine kunapangitsa kuti pakhale nthawi yofanana ya analgesia, yokhala ndi mbali yayikulu ya kumbuyo ataxia (100% incidence). Tidazindikira kuti xylazine yoperekedwa ndi jakisoni wa epidural imapangitsa kuti pakhale ma analgesia otetezeka, ogwira ntchito pamahatchi [2].

Xylazine hydrochloride Biological Activity

Kufotokozera Xylazine Hydrochloride ndi α2 kalasi ya adrenergic receptor agonist. Zolinga: Adrenergic ReceptorXylazine ndi mankhwala omwe amagwiritsidwa ntchito kutontholetsa, kupweteka, kupuma kwa minofu, ndi analgesia mu nyama monga akavalo, ng'ombe ndi nyama zina zopanda anthu. Analog ya clonidine, ndi agonist mgulu la α2 la adrenergic receptor. Xylazine posachedwapa yatulukira ngati mankhwala osangalatsa, makamaka ku Puerto Rico [1]. Kuyendetsa xylazine (0.17 mg / kg ya kulemera kwa thupi, kuchepetsedwa mpaka voliyumu ya 10-ml, pogwiritsa ntchito 0.9% NaCl) kumapangitsa pafupifupi maola 2.5 a analgesia am'deralo popanda zovuta zina. Mlingo wambiri wa xylazine unachititsa kuti kumbuyo kwa ataxia kofatsa. Kulamulira kwa lidocaine kunapangitsa kuti pakhale nthawi yofanana ya analgesia, yokhala ndi mbali yayikulu ya kumbuyo ataxia (100% incidence). Tidazindikira kuti xylazine yoperekedwa ndi jakisoni wa epidural imapangitsa kuti pakhale ma analgesia otetezeka, ogwira ntchito pamahatchi [2].
Catalog Yofanana
Zolemba [1]. Reyes, JC, et al., Kutuluka kwa xylazine ngati mankhwala osokoneza bongo komanso zovuta zake pakati pa ogwiritsa ntchito mankhwala ku Puerto Rico. J Urban Thanzi, 2012. 89 (3): p. 519-26.[2]. Hsu, WH, Xylazine-yomwe idapangitsa kukhumudwa komanso kutsutsana kwake ndi ma alpha adrenergic blocking agents. J Pharmacol Exp Ther, 1981. 218 (1): p. 188-92.

Mankhwala & Katundu Wathupi

Kuchulukitsitsa 1.15g / cm3
Malo Otentha 334.2ºC pa 760mmHg
Kusungunuka 150-164? C (Dec.)
Makhalidwe a Maselo C12H17ClN2S
Kulemera kwa Maselo Zamgululi
Pophulikira 155.9ºC
Misa yeniyeni Zamgululi
PSA 49.69000
LogP 3.51880
Vapor Anzanu 0.00013mmHg pa 25 ° C
Mkhalidwe wosungira -20 ° C

Zambiri Zokhudza Poizoni

KUDZIWIKITSA CHIKHALIDWE

Nambala ya RTECS:
XJ0776350
DZIKO LANTHAWI:
4H-1,3-Thiazine, 5,6-dihydro-2- (2,6-xylidino) -, monohydrochloride
Nambala YOLEMBETSA CAS:
23076-35-9
ZINASINTHIDWA KWAMBIRI:
199609
ZINTHU ZOFUNIKA KUCHITIKA:
4
FOMU YOPHUNZITSIRA:
Gawo #: C12-H16-N2-S. Cl-H
Kulemera kwa molekyulu:
Zamgululi
WISE-WERI MFUNDO DZIWANI:
Opanga: T6N CS AUTJ BMR B1 F1 & GH

DATA DZIWANI ZAUMOYO

DZIWANI ZOTHANDIZA PAMODZI

MTUNDU WA KUYESA:
TDLo - Mlingo woopsa kwambiri wofalitsidwa
NTHAWI YA KUVUMBULIDWA:
Mitsempha
NKHANI ZOONETSEDWA:
Munthu - munthu
Mlingo / nthawi:
14 mg / kg
ZOTSATIRA ZA MPHAMVU:
Khalidwe labwino - kukomoka kwa Mtima - EKG imasintha osazindikira zotsatira zamapapo, Thorax, kapena Kupuma - kusintha kwina
ZOKHUDZA:
CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. Kuti mumve zambiri, onani JTCTDW. Voliyumu (nkhani) / tsamba / chaka: 15,281,1979
MTUNDU WA KUYESA:
LD50 - Mlingo wa Lethal, 50% amapha
NTHAWI YA KUVUMBULIDWA:
Mitsempha
NKHANI ZOONETSEDWA:
Mbewa - mbewa
Mlingo / nthawi:
109 mg / kg
ZOTSATIRA ZA MPHAMVU:
Zambiri zakupha poyizoni zomwe sizinafotokozedwe kupatula phindu lakupha
ZOKHUDZA:
ZYYZEW Zhongguo Yaolixue Yu Dulixue Zazhi. (Chinese Pharmacological Society, 27 Tai-Ping Road, Beijing 100850, China) V.1- 1986- Vuto (nkhani) / tsamba / chaka: 9,96,1995
MTUNDU WA KUYESA:
LD50 - Mlingo wa Lethal, 50% amapha
NTHAWI YA KUVUMBULIDWA:
Mitsempha
NKHANI ZOONETSEDWA:
Zinyama - galu
Mlingo / nthawi:
47 mg / kg
ZOTSATIRA ZA MPHAMVU:
Zambiri zakupha poyizoni zomwe sizinafotokozedwe kupatula phindu lakupha
ZOKHUDZA:
CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. Kuti mumve zambiri, onani JTCTDW. Voliyumu (nkhani) / tsamba / chaka: 15,281,1979
MTUNDU WA KUYESA:
LD50 - Mlingo wa Lethal, 50% amapha
NTHAWI YA KUVUMBULIDWA:
Mitsempha
NKHANI ZOONETSEDWA:
Rodent - nkhumba ya Guinea
Mlingo / nthawi:
10 mg / kg
ZOTSATIRA ZA MPHAMVU:
Zambiri zakupha poyizoni zomwe sizinafotokozedwe kupatula phindu lakupha
ZOKHUDZA:
VHTODE Chowona Zanyama ndi Toxicology ya Anthu. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume (nkhani) / tsamba / chaka: 24,410,1982

Mawu ofanana

BAY 1470 hydrochloride
Xylazine mankhwala enaake
2- (2,6-Dimethylphenylamino) -5,6-dihydro-4H-thiazine hydrochloride
2 - [(2,6-Dimethylphenyl) amino] -5,6-dihydro-4H-1, 3-thiazine Hydrochloride
N- (2,6-Dimethylphenyl) -5,6-dihydro-4H-1,3-thiazin-2-amine hydrochloride (1: 1)
BAY VA 1470
EINECS 245-417-0
4H-1,3-Thiazin-2-amine, N- (2, 6-dimethylphenyl) -5,6-dihydro-, hydrochloride (1: 1)
Wopanda
N- (2,6-Dimethylphenyl) -5, 6-dihydro-4H-1,3-thiazin-2-amine hydrochloride
Xylazine HCl
Chidwi

 

 

 

 





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